International Review of Ophthalmology ›› 2021, Vol. 45 ›› Issue (4): 312-317.doi: 10.3760/ cma.j.issn.1673-5803.2021.04.008

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Association between dyslipidemia and mebomian gland dysfunction

Shi Yu1，Zeng Qingyan 2,3,4   

  1. 1 First Clinical College of Wenzhou Medical University, Wenzhou 325035, China; 2 Hankou Hospital, Wuhan Aier Eye Hospital, Wuhan 430020, China; 3 Hubei University of Science and Technology, Xianning 437100, China; 4 Aier Cornea Disease Institute, Beijing 100600, China
  • Received:2020-08-26 Online:2021-08-22 Published:2021-08-30
  • Contact: Zeng Qingyan, Email: zengqingyan1972@163.com E-mail:zengqingyan1972@163.com
  • Supported by:
    Aier Eye Hospital Group Research Fund (AR1904D2)

Abstract: Clinical studies have shown that there is a close correlation between dyslipidemia and mebomian gland dysfunction(MGD). Higher serum total cholesterol (TC), triglyceride (TG) and low density lipoprotein (LDL) can promote the development of MGD. Studies have found that elevated high density lipoprotein (HDL) can lead to the progression of MGD. It was found by animal experiments that dyslipidemia may lead to various pathological changes of meibomian glands. Some lipid-lowering drugs also have some therapeutic effects on MGD. (Int Rev Ophthalmol, 2021, 45: 312-317)

Key words: dyslipidemia, meibomian gland dysfunction